Informatics Publishing Limited

R. S. Jagtap ¹

Affiliations
1 Central Water and Power Research Station (Government of India), Pune 412 303, IN

Abstract

Risk of possible damage to important hydraulic structures needs to be kept at the minimum by suitably modelling environmental parameters like rainfall for extreme values of desired return period. Efficient estimation of such meteorological extremes depends on the historical records available at the site of interest. Each of the sampled data is essentially a signal from the natural system and in any statistical analysis uncertainty about the underlying phenomenon gets reduced with increase in the record length. In this article, the effect of record length on the extreme value estimates of daily rainfall at Colaba and Santacruz using theoretically appropriate generalized extreme value (GEV) model has been analysed. The study indicates that estimates for different return periods get stabilized with the increase in the length of record. Data analysis-based recent past records at Colaba give comparatively higher estimates which can possibly be attributed to increased variation and observance of more number of extreme events during the recent past. The heavy rainfall of 944.2 mm recorded at Santacruz on 26 July 2005 has shown an extraordinary effect on extreme value estimates. A possibility of temporal dependence in the series requires further studies by parameterization of trend in the GEV model.

Keywords

Extreme Precipitation Analysis, Generalized Extreme Value Model, Hydraulic Structures, Return Level, Return Period.

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Deepak Bharati ¹, R. S. Jagtap ¹, K. G. Kanase ¹, S. A. Sonawame ¹, V. R. Undale ¹, A. V. Bhosale ¹

Affiliations
1 S.G.R.S College of Pharmacy, Saswad, Pune-413302, Maharashtra, IN

Abstract

Chemo informatics is a scientific discipline that has evolved in the last 40 years at the interface between chemistry and computer science. It has been realized that in many areas of chemistry, the huge amount of data and information produced by chemical research can only be processed and analyzed by computer methods. Furthermore, many of the problems faced in chemistry are so complex that novel approaches utilizing solutions that are based on informatics methods are needed. Thus, methods were developed for building databases on chemical compounds and reactions, for the prediction of physical, chemical and biological properties of compounds and materials, for drug design, for structure elucidation, for the prediction of chemical reactions and for the design of organic syntheses.

Keywords

Chemi Informatics, Drug Development, Structure Activity Relationship.

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